2nd ICCA MARII Workshop
12.06.2023 - 14.06.2023
New Task Force on Chemical Risk Assessment of Plastic Additives
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New Task Force on Chemical Risk Assessment of Plastic Additives

To support safer assessments of plastic additives and associated chemicals, ECETOC just launched a Task Force dedicated to evaluating the state of the science and applying risk assessment principles t...
Launching Soon: Polymer Analytics Task Force
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Launching Soon: Polymer Analytics Task Force

ECETOC is launching the Polymer Analytics Task Force to develop and standardize methods for analysing polymer properties essential for safety assessment. This initiative comes in response to the growi...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
Dose Selection Task Force

Dose Selection Task Force

Background Recent opinions published by the RAC on low top dose selection in animal toxicity studies have indicated an apparent intent of increasing dosages systematically in view of the criteria u...
Mid-tier approach to aggregated exposure assessment TF

Mid-tier approach to aggregated exposure assessment TF

Background There are increasing public and regulatory concerns regarding potential health risks posed by aggregate exposure, i.e. exposure to (the same) substance from multiple sources via multiple...
Moving persistence (P) assessments into the 21st Century: Developing a new paradigm to assess degradation potential of chemicals

Moving persistence (P) assessments into the 21st Century: Developing a new paradigm to assess degradation potential of chemicals

Background Recent progress in the scientific understanding of the underlying processes of persistence and degradation has provided an opportunity to develop an improved framework and best practices...

Endocrine DisruptorsBisphenol A (BPA)

Publications

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DOC 034 – The Challenge Posed by Endocrine Disrupting Chemicals

DOC 034 : The Challenge Posed by Endocrine-disrupting Chemicals | February 1996 ...
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DOC 033 – “Environmental Oestrogens” : A compendium of Test methods

DOC 033 : 'Environmental Oestrogens': A Compendium of Test Methods | July 1996Against a background of increasing concern about the potential for natural and synthetic chemicals to affect reproduct...
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DOC 032 – “Environmental Oestrogens”: Male Reproduction and Reproductive Development

DOC 032 : 'Environmental Oestrogens': Male Reproduction and Reproductive Development | January 1998The paper was developed to review the currently available data relevant to the putative effects o...
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Monograph 005 – Identification and Assessment of the Effects of Chemicals on Reproduction and Development (Reproductive Toxicology)

Mono 005 : Identification and Assessment of the Effects of Chemicals on Reproduction and Development (Reproductive Toxicology) | December 1983...
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DOC 013 – The Organisation of Jointly-Sponsored (ECO) Toxicological Studies

DOC 013 : The Organisation of Jointly-Sponsored (Eco)Toxicological Studies| December 1980ECETOC members sometimes participate in (eco) toxicological studies, jointly sponsored at a contract labora...
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DOC 012 – Criteria for Choosing Chemicals for Testing

DOC 012 : Criteria for Choosing Chemicals for Testing | December 1980...

Task Forces

Substances that activate various liver receptors as endocrine disruptors

Substances that activate various liver receptors as endocrine disruptors

Why? The current development of NAMs in the field of endocrine disruption (ED) is very active as the concept of ED is evolving in various areas of toxicology including liver toxicity/xenobiotic met...